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Magnesium Oxide vs Magnesium Glycinate

When it comes to magnesium supplements, you might come across the debate of magnesium oxide vs magnesium glycinate.
Both are popular forms of magnesium, but they have distinct differences in how they work in the body.
Understanding these differences can help you make an informed choice about which supplement is best for your health goals.
Whether you're interested in boosting your sleep quality, supporting muscle function, or improving digestive health, knowing the key benefits of these two forms of magnesium will guide your decision.
What this article covers:
- Understanding Magnesium Supplements
- Magnesium Oxide: Overview and Benefits
- Magnesium Glycinate: Overview and Benefits
- Magnesium Oxide vs Magnesium Glycinate: Key Differences
- Which Magnesium Supplement is Right for You?
Understanding Magnesium Supplements
What is Magnesium?
Magnesium is an essential mineral that plays a critical role in hundreds of bodily functions. It's involved in processes like muscle and nerve function, bone health, energy production, and regulating blood sugar.
Magnesium is found naturally in foods like leafy greens, nuts, seeds, and whole grains.
However, many people still struggle to get enough from their diet alone, which is where supplements like magnesium oxide and magnesium glycinate (otherwise known as magnesium bisglycinate) come into play.
Why is Magnesium Important for Health?
Magnesium is crucial for a variety of reasons. It helps regulate muscle and nerve function, supports a healthy immune system, and maintains normal heart rhythm.
Magnesium also helps regulate blood pressure, contributing to overall cardiovascular health.
Since it's involved in so many essential processes, magnesium deficiency can lead to symptoms like muscle cramps, fatigue, and poor sleep.
That's why many people turn to magnesium supplements to ensure they're meeting their daily requirements.
Magnesium Oxide: Overview and Benefits
What is Magnesium Oxide?
Magnesium oxide is one of the most common and affordable forms of magnesium available. It's often used in supplements and is also found in many over-the-counter medications for heartburn and indigestion.
This form of magnesium has a relatively low bioavailability, which means it's not as easily absorbed by the body as some other forms, like magnesium glycinate.
Key Benefits of Magnesium Oxide
Magnesium oxide is commonly used for its benefits in supporting digestive health, especially for relieving constipation.
It can also help with acid reflux and indigestion by neutralising stomach acid. This makes it a popular choice for people seeking digestive support.
Common Uses of Magnesium Oxide
As mentioned, magnesium oxide is often used to support digestive health, but it also has other applications.
It can be found in supplements aimed at providing overall magnesium supplementation.
It's also commonly used in laxatives to relieve constipation, as it draws water into the intestines, promoting bowel movements.
Magnesium Oxide's Bioavailability and Absorption
The bioavailability of magnesium oxide is relatively low. This means that while you may be taking magnesium oxide, only a portion of it will be absorbed by the body.
This can make it less effective for people looking to quickly boost their magnesium levels.
However, magnesium oxide is still useful for digestive health and other applications where it's needed in larger doses.
Magnesium Glycinate: Overview and Benefits
What is Magnesium Glycinate?
Magnesium glycinate is a highly bioavailable form of magnesium, meaning it is better absorbed by the body compared to magnesium oxide.
It's made by combining magnesium with glycine, an amino acid. This form is often preferred for its calming and relaxing properties, as glycine is known for promoting restful sleep and reducing stress.
Key Benefits of Magnesium Glycinate
Magnesium glycinate is a great option for those looking to improve their sleep, reduce stress, and support overall muscle function.
It is also commonly used to help with symptoms of magnesium deficiency, such as cramps, fatigue, and muscle spasms.
The calming effect of magnesium glycinate also makes it a go-to choice for people with anxiety or those who struggle to relax before bed.
Common Uses of Magnesium Glycinate
Magnesium bisglycinate is often used by individuals seeking better sleep quality, relief from anxiety, and support for muscle function.
It's also a popular choice for people with a sensitive stomach, as it's gentler than other forms like magnesium citrate or oxide.
Magnesium Glycinate's Bioavailability and Absorption
Magnesium glycinate has excellent bioavailability, meaning the body can absorb it more efficiently.
This makes it a better option for those who want to ensure they're getting the full benefits of their magnesium supplement.
Because of its high absorption rate, magnesium glycinate is often considered one of the best forms of magnesium for therapeutic use.

Magnesium Oxide vs Magnesium Glycinate: Key Differences
Absorption and Bioavailability
The main difference between magnesium oxide vs magnesium glycinate lies in how well they are absorbed by the body.
Magnesium glycinate is far superior in this regard due to its high bioavailability.
In contrast, magnesium oxide has a much lower absorption rate, which can make it less effective for increasing magnesium levels quickly.
If you're looking for maximum absorption, magnesium glycinate is your best bet.
Effectiveness for Different Health Conditions
When it comes to effectiveness, magnesium glycinate tends to be more beneficial for managing symptoms like anxiety, stress, and insomnia.
Its calming properties are ideal for people who struggle with sleep or need help winding down at the end of the day.
On the other hand, magnesium oxide is more commonly used for digestive support, such as relieving constipation or acid reflux.
It's also an affordable option for those looking to manage their magnesium levels without needing a high dose.
Side Effects and Tolerability
In general, magnesium glycinate is better tolerated than magnesium oxide. Magnesium oxide can cause gastrointestinal issues like bloating, gas, and diarrhoea, especially when taken in high doses.
Magnesium glycinate, due to its gentle nature, is less likely to cause these side effects, making it a safer option for people with sensitive stomachs.
Cost and Availability
Magnesium oxide is often more affordable and widely available in Canada, making it a popular choice for those on a budget.
Magnesium bisglycinate, while more expensive, provides superior benefits in terms of absorption and effectiveness, which may justify the higher price for some individuals.
Which Magnesium Supplement is Right for You?
Choosing Based on Health Goals
When deciding between magnesium oxide and magnesium glycinate, it's important to consider your specific health goals.
If you're looking for digestive support, magnesium oxide is a great choice due to its laxative properties.
However, if you're looking for something that promotes relaxation, better sleep, and muscle health, magnesium glycinate is likely the better option.
If you're looking for a premium magnesium bisglycinate product, look no further than VitaCheck Magnesium Bisglycinate 200mg.
This high-quality supplement offers 200mg of bioavailable magnesium per capsule, ensuring optimal absorption and maximum benefits.
With 120 vegetable capsules in each bottle, it supports muscle relaxation, reduces fatigue, and promotes overall well-being.
Perfect for anyone seeking a gentle yet effective way to boost magnesium levels, this product is a must-have for your daily routine.
Magnesium for Sleep, Stress, and Muscle Health
For sleep support, stress relief, and muscle health, magnesium glycinate is highly recommended.
It's gentle on the stomach and provides a calming effect, which is ideal for winding down before bed or managing anxiety.
Magnesium for Digestive Health
If you're dealing with constipation or acid reflux, magnesium oxide might be the better choice. Its ability to draw water into the intestines makes it effective for relieving constipation.
However, for daily magnesium supplementation, magnesium glycinate is often a better option for those with sensitive stomachs.

Factors to Consider When Choosing a Supplement
When choosing between magnesium oxide vs magnesium glycinate, consider factors such as your health goals, budget, and tolerance.
Magnesium glycinate may be more expensive, but it offers better absorption and fewer side effects.
Magnesium oxide is a more affordable option but may not provide as many benefits for general magnesium supplementation.
Conclusion
In the debate of magnesium oxide vs magnesium glycinate, the right choice depends on your specific health needs.
Magnesium glycinate offers superior absorption and is ideal for improving sleep, reducing stress, and supporting muscle health. Magnesium oxide, while less expensive, is better suited for digestive health.
At Vitamart, we offer a range of magnesium supplements to meet your needs, whether you're looking for digestive support or overall wellness.
Check out our detailed guides if you're curious about magnesium gluconate vs glycinate, magnesium malate vs bisglycinate or pantoprazole sodium vs magnesium. We've got you covered!
For more information on magnesium supplements, visit our website today.
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